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🧩 Major review finds Prozac offers no real benefit for children A new analysis of 12 trials involving more than 1,500 children and adolescents shows fluoxetine (Prozac) works no better than placebo, with effect sizes close to zero. Researchers say early studies overstated benefits due to small samples and bias, while newer, larger trials show clinical equivalence and little measurable improvement in mood or functioning. Placebo-response rates were high, making the drug–placebo gap even smaller,
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