The Evolution of Exercise with Dr. Daniel E. Lieberman AB '86, PhD '93

The real issue for guys running multiple cycles a year isn’t the compounds, it’s the constant hormonal whiplash. Blast → come off → crash testosterone → spike LH/FSH → feel like shit → jump back on and shut it all down again. Every time you fully come off, you’re forcing the HPTA to restart under stress, inflammation, and depleted recovery capacity. That’s when you see mood swings, libido issues, poor sleep, anxiety, and blood markers drifting further out of range each time. Backing down to a TR