Eagles hoping to improve position in NFC playoff structure unveil injury report with 4 players listed including AJ Brown

This article was originally published on www.si.com/nfl/bills/onsi as Former All-Pro chooses between Josh Allen, Jalen Hurts ahead of Bills-Eagles matchup.

The defending Super Bowl champs, the Eagles have rebounded from a three-game losing streak to win their last two and, in the process, repeat as NFC East champions. Philly is the first team in the division to repeat since they did it back in 2004. It snapped the longest streak without a repeat champ by any division in NFL history.

The Philadelphia Eagles take on the Buffalo Bills on Sunday, Dec. 28, 2025. Here's how to watch pregame and postgame coverage on NBC10.

Sal Maiorana’s take: The Bills have two key advantages: they’re at home and the game matters more for their playoff hopes. Buffalo is 16-1 at home since early 2024, while the Eagles—already locked into at least the No. 3 NFC seed—are strong on the road (5-3). It’ll be tough, but Sal believes the Bills will pull it off.

The Philadelphia Eagles enter their Week 17 matchup with the Buffalo Bills relatively healthy at this point in the season. The Bills have a long list of players on IR, as well as on their injury report this week. Here's the Eagles-Bills injury report, with analysis.

Cooper DeJean earned the NFC Defensive Player of the Week award after a standout performance against the Washington Commanders.

The stakes are high for several teams in the penultimate week of the NFL regular season. Here's how the odds see it going.