A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

New 3D genome maps reveal how DNA folding controls gene activity, offering fresh clues into disease and cell function.

Researchers created the most detailed maps yet of the genome’s three-dimensional organization using human stem cells and ...

A new study shows, for the first time, how the human genome folds and moves in 3D over time to control when genes turn on and ...

If stretched out, human DNA would be about 2 meters long. For this long strand to fit inside the cell nucleus, which is about ...

Researchers from Miguel Hernández University of Elche (UMH) in Spain have identified an effective strategy to reduce ...

It's a common storytelling trope: the stubborn foe who is eventually revealed to be a much-needed friend. Biology has its own ...

CpG density and epigenetic modification state modulate DNA mechanics, altering its intrinsic compatibility with nucleosome formation.

Researchers at the CNIO show that oestrogens regulate gene expression by changing DNA supercoiling. Hormone-activated ...

A new study challenges what's long been assumed about genetic variants thought to always cause inherited blindness.