This Viral RNA Structure Could Lead to a Universal Antiviral Drug

Researchers identify a shared RNA-protein interaction that could lead to broad-spectrum antiviral treatments for enteroviruses ...
Baylor College of Medicine

Researchers show benefit of ultra-deep RNA sequencing in Mendelian disorder diagnostics

RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this technology has not yet been determined. In a new study published in the ...
C&EN

Single-Molecule Sequencing of RNA

What biological questions can single-molecule RNA sequencing help address that traditional methods cannot? How can these technologies be applied in your area of research, and what limitations might ...
Baylor College of Medicine

Baylor researchers develop and validate clinical diagnostic RNA sequencing test

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...
FierceBiotech

Roche rolls out new DNA 'sequencing-by-expansion' approach

Roche has put forward a new approach to genetic analysis, which it describes as sequencing-by-expansion—a proprietary method that pulls apart the DNA molecule and amplifies the signal of each ...
C&EN

Researchers can identify a person by sequencing RNA from individual cells

An individual’s genome is identifiable. But datasets of RNA sequences from single cells are like a blurry photocopy of the genome. The sequence numbers are small, the data are noisy, and the sequences ...
Hosted on MSN

Video tutorial: How to make bone broth for your dogs

This bone broth is good for you and your dog. Domestic violence victim uses hand signals to ask for help: Police Donald Trump responds to object thrown out of White House window King Charles Returns ...
eLife

Robust single-nucleus RNA sequencing reveals depot-specific cell population dynamics in adipose tissue remodeling during obesity

So et al. present an optimized protocol for single-nuclei RNA sequencing of adipose tissue in mice, ensuring better RNA quality and nuclei integrity. The authors use this protocol to explore the ...
Hosted on MSN

Carnell Stomp Tutorial!

Donald Trump gives update on "Arc de Trump" Lady Gaga abruptly stops Mayhem Ball show mid-performance after dancer falls off stage in Australia A Florida town and its very expensive legal fight to ...
Frontiers

Integrated single-cell RNA sequencing reveals the tumor heterogeneity and microenvironment landscape during liver metastasis in adenocarcinoma of esophagogastric junction

1 Department of General Surgery, First Affiliated Hospital of Anhui Medical University, Hefei, China 2 Department of Thoracic Surgery, First Affiliated Hospital of Anhui Medical University, Hefei, ...
eLife

An improved bacterial single-cell RNA-seq reveals biofilm heterogeneity

This work introduces an important new method for depleting ribosomal RNA from bacterial single-cell RNA sequencing libraries, demonstrating its applicability for studying heterogeneity in microbial ...