eLife

Functional genomics reveals strain-specific genetic requirements conferring hypoxic growth in Mycobacterium intracellulare

Transposon sequencing analyses reveal that among genomically diverse clinical Mycobacterium intracellulare strains and the type strain, 131 genes were comprehensively identified as universal essential ...
IEEE

Cyber-Biosecurity Challenges in Next-Generation Sequencing: A Comprehensive Analysis of Emerging Threat Vectors

Abstract: Next-generation sequencing (NGS) has transformed genomic research and healthcare by enabling the rapid and cost-effective sequencing of DNA and RNA, surpassing traditional techniques such as ...
Frontiers

Circulating microbiome profiling in transjugular intrahepatic portosystemic shunt patients: 16S rRNA vs. shotgun sequencing

Background and aim: Current efforts to characterize the circulating microbiome are constrained by the lack of standardized protocols for isolating and sequencing microbial communities in blood. To ...
Frontiers

Investigation for atherosclerotic plaque rupture with thrombosis in mice based on single-cell sequencing and bioinformatics analysis

1 Division of Cardiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China 2 Department of Laboratory Animal Science, Shanghai Jiao Tong University School of Medicine, ...