Scientists at St. Jude Children's Research Hospital and Northwestern University identified a previously unknown treatment opportunity for sickle cell disease and β-thalassemia. The discovery, ...

Department of Cellular and Developmental Biology of Plants, University of Bielefeld, Bielefeld, Germany Algae inhabit diverse environments with highly variable light conditions, making light sensing ...

Three draft recommendation documents published on Wednesday are intended to guide drug sponsors and accelerate the development of cell and gene therapies. The FDA has published three draft ...

A federal appeals court on Friday ruled against President Trump’s effort to cut billions of dollars of foreign aid that was previously approved by Congress through “pocket rescissions.” The U.S. Court ...

Single cell gene expression studies often rely on single-cell RNA sequencing (scRNA-seq) alone. While scRNA-seq reveals which genes are turned on, it does not capture protein expression or changes to ...

A research team headed by the University of Zurich has developed a powerful new method to precisely edit DNA by combining cutting-edge genetic engineering with artificial intelligence. The work has ...

This story is the first in an occasional series following Louisiana’s first patients to receive gene therapy for sickle cell disease. On the third floor of Manning Family Children’s Hospital in New ...

The Centers for Medicare & Medicaid Services (CMS) announced Tuesday that 33 states, as well as the District of Columbia and Puerto Rico, have agreed to participate in the Cell and Gene Therapy (CGT) ...

In biology classrooms, we often learn that genes are transcribed into mRNA, which is then translated into proteins—a tidy, linear process. But gene expression in living cells is far more intricate, ...

Researchers in the lab of Hans-Peter Kiem, MD, PhD, at Fred Hutch Cancer Center have devised a method that could one day treat genetic hematologic disorders by correcting how the body makes blood ...

For stem cells to differentiate into the appropriate cell-type, transcription factors (TFs) must be tailored to highly specific expression patterns of lineage-specific genes. Abnormalities in the ...