Cell membrane integrity is vital for the survival and function of tissues across biological systems. The rapid repair of membrane disruptions is mediated by specialised mechanisms that mobilise ...

Researchers at UT Southwestern Medical Center have identified a protein that causes human cell membranes to break open in a form of inflammatory programmed cell death called necroptosis. Their ...

To ensure that protein production in our cells runs smoothly, the protein complex NAC slows down the rate of protein ...

Membraneless organelles, also called biomolecular condensates, are changing how scientists think about protein chemistry, ...

Scientists have discovered that T cell receptors activate through a hidden spring-like motion that had never been seen before ...

When a cell receives a message from outside, it generates a molecule called cyclic AMP (cAMP) to relay this message. To ensure the signal reaches the correct effector without triggering pathways ...

Many biological processes are regulated by electricity—from nerve impulses to heartbeats to the movement of molecules in and ...

A hidden “jack-in-the-box” mechanism inside T cells may hold the key to unlocking more powerful cancer immunotherapies.

Scientists organize millions of proteins by shape, as predicted by AI, revealing 700,000 new families and some shapes unique ...

Scientists have identified a small flaw in the enzyme GPX4 that prevents neurons from defending themselves. This mutation, ...