A new CRISPR approach can control genes without cutting DNA, opening a safer path for treating genetic diseases. A newly developed form of CRISPR at UNSW Sydney points to a safer way of treating ...

This study presents SynaptoGen, a differentiable extension of connectome models that links gene expression, protein-protein interaction probabilities, synaptic multiplicity, and synaptic weights, and ...

Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy by harnessing the body's immune system to target ...

Artificial intelligence has just redrawn the map of our genome’s control room, revealing hundreds of thousands of tiny DNA ...

Scientists have long known that mutations in certain genes affecting microtubules in plants can cause plants to grow in a twisting manner. In most cases, these are “null mutations,” meaning the ...

Although it also performs some functions in men, estrogen, the main female sex hormone, is involved in a myriad of processes, ...

It's a common storytelling trope: the stubborn foe who is eventually revealed to be a much-needed friend. Biology has its own ...

Analyzing stochastic cell-to-cell variability can potentially reveal causal interactions in gene regulatory networks.

Cell and gene therapy (CGT) has evolved from a niche research pursuit into a central force in biopharmaceutical innovation. By engineering living cells and genetic material to repair or replace faulty ...

Common variants in the phosphoinositol phosphatase INPP5D are linked to an increased risk of late-onset Alzheimer’s disease, but no one is quite sure why. Recent work suggests that depleting INPP5D in ...

Silence Therapeutics designs and develops siRNAs (short interfering RNAs) to address unmet patient need across a wide range of diseases with a genetic basis. In this interview with STAT Brand Studio, ...

This book is a lab manual that can be integrated with a bioinformatics course. The field of bioinformatics is advancing at a remarkable rate. With the development of new analytical techniques that ...