PLAMseq utilizes a rapid biotinylation enzyme called TurboID, which tags nearby proteins, enabling the genomic loci and ...
High-resolution imaging has revealed the internal layout of chromatin condensates, showing how DNA fibers fold and interact within these droplet-like structures. The findings connect molecular ...
New ultra-detailed imaging exposes the hidden structure and behavior of chromatin condensates — and hints at how their failures may drive disease.
A game-changining achievement in genome science has identified over 140,000 distinct DNA loops in our cells, providing chromosome fold resolution that is among the best ever created. In this ongoing ...
Figure 1: Sequence alignment of human, mouse, zebrafish and C. elegans BAF, together with a summary of the secondary structure. With only three exceptions comprising conservative substitutions ...
Inside every human cell, six feet of DNA folds into a nucleus that is only a few micrometers wide, yet still manages to switch genes on and off with exquisite precision. The latest work on ...
The Mahindra Construction Equipment business boasts of the popular Mahindra RoadMaster Motor Grader, designed to deliver ...
CpG density and epigenetic modification state modulate DNA mechanics, altering its intrinsic compatibility with nucleosome formation.
Figure 1: Sequence and secondary structure elements of the Sso7d protein from Sulfolobus solfataricus. Figure 2: Scatchard plot based on a titration of GC3 DNA on Sso7d. Figure 4: Illustration of the ...
DNA methylation involves adding a methyl group to DNA, which may influence gene expression and affect health aspects like childhood development and aging. Lifestyle factors, especially diet, may ...