One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

The complete assembly of each human chromosome is essential for understanding human biology and evolution. Using complementary long-read sequencing technologies, we complete the first linear assembly ...

We are entering into an exciting era of genomics where truly complete, high-quality assemblies of human chromosomes are available end-to-end, or from ‘telomere-to-telomere’ (T2T). Recently, the ...

From morning glories spiraling up fence posts to grape vines corkscrewing through arbors, twisted growth is a problem-solving ...

The genetic heritage is not a simple, static list inside the cell nucleus. It unfolds into a dynamic architecture whose intimate folds govern the destiny of cells. A mapping of ...

A game-changining achievement in genome science has identified over 140,000 distinct DNA loops in our cells, providing chromosome fold resolution that is among the best ever created. In this ongoing ...

After 10 years, members of the 4D Nucleome consortium have successfully completed the first phase of a project that aims to ...