If stretched out, human DNA would be about 2 meters long. For this long strand to fit inside the cell nucleus, which is about ...
Study finds CRISPR/Cas gene editing causes “chromatin fatigue” – another surprise mechanism by which it can produce unwanted ...
There is a huge amount of DNA in most human cells, and that DNA has to be carefully compacted and organized so that it will ...
Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and ...
Myelodysplastic syndrome (MDS) arises from defective blood stem cells that progressively lose their normal functions.
Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and ...
DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes.
A quick revision guide covering key concepts, biomolecules, cell organelles, and essential NEET-style MCQs to boost exam preparation.
High-resolution imaging has revealed the internal layout of chromatin condensates, showing how DNA fibers fold and interact within these droplet-like structures. The findings connect molecular ...
New ultra-detailed imaging exposes the hidden structure and behavior of chromatin condensates — and hints at how their failures may drive disease.
We are grateful to Prof. Shuhua Xu (Fudan University) for sharing the Fiber-seq protocol. We thank Prof. Peter Quail (University of California, Berkeley) for providing pifqseeds. This work was ...
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