No more Kegels: I found a fix for post-birth incontinence – why don’t more women know about it?

After years of worrying that running or sneezing would leave me needing fresh underwear, a quick procedure changed my life ...
eLife

A differentiable model for optimizing the genetic drivers of synaptogenesis

This study presents SynaptoGen, a differentiable extension of connectome models that links gene expression, protein-protein interaction probabilities, synaptic multiplicity, and synaptic weights, and ...
eLife

Translational reading frame determines the pathogenicity of C-terminal frameshift deletions in MeCP2: an alternative therapeutic approach

This study offers important insight into the pathogenic basis of intragenic frameshift deletions in the carboxy-terminal domain of MECP2, which account for some Rett syndrome cases, yet similar ...
BMJ Open

Enhancing the use of economic evidence in vaccination policy and decision making in low- and middle-income countries: a scoping review of existing strategies

Objectives The use of economic evidence to prioritise vaccines and delivery strategies to optimally use in immunisation systems is becoming a global priority, especially in low- and middle-income ...

Browns bank on spoiling Steelers' celebration

Tomlin sounds more interested in seeing his defense deliver as it did last week against the Lions, stuffing Jahmyr Gibbs and David Montgomery consistently in a 29-24 victory. The Steelers held the ...