Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and differentiation sustains healthy blood formation. In myelodysplastic ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

Myelodysplastic syndrome (MDS) arises from defective blood stem cells that progressively lose their normal functions. Japanese researchers have revealed how changes in chromatin accessibility—how DNA ...

New 3D genome maps reveal how DNA folding controls gene activity, offering fresh clues into disease and cell function.

Researchers created the most detailed maps yet of the genome’s three-dimensional organization using human stem cells and ...

Professor Yohan Kim of Sungkyunkwan University and the Max Planck Institute research team recreated the structure and ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

The research represents a major step forward in revealing how the three dimensional form of DNA shapes the way human biology functions. In a major step toward understanding how the physical form of ...

Osteoarthritis is one of the most expensive and disabling conditions in modern medicine, driving joint replacements and ...

A new study in the lab of Jason Stein, Ph.D., modeled brain development in a dish to identify cells and genes that influence ...

Researchers have made great strides to understand early signs of autism.Studies have found that certain factors like genetics, sleep deprivation ...