As neuronal supporters and immune surveyors, astrocytes and microglia are no mere bystanders to the neuronal mayhem that unfolds in Alzheimer’s disease. At the AD/PD meeting, held March 5-9 in Lisbon, ...

The idea that infiltrating T cells contribute to a neurodegenerative environment in aging and in Alzheimer’s disease has gotten another boost. In the June 27 Nature Neuroscience, scientists led by ...

Microglia are known to play an important role in Alzheimer's disease, but exactly what they do has remained a mystery. Scientists in the Bart De Strooper Lab at the VIB-KU Leuven Center for Brain & ...

Microglia have distinct morphologies depending on where they reside in the mouse brain, according to a novel approach that reveals nuances about the cells’ shape. That form also changes with ...

It’s hard to overstate how crucial microglia are to brain health. These humble immune cells quietly patrol the central nervous system, clearing debris, pruning synapses, and maintaining myelin. But ...

In a recent review published in Experimental & Molecular Medicine, researchers reviewed existing data on the neurodegenerative effects of astrocyte-derived lipocalin-2 (LCN-2). Study: Lipocalin-2: a ...

Low-grade inflammation contributes to age-related decline and impairment, but the precise pathways responsible for this inflammation and their impact on natural aging have until now remained elusive.

New data on oral minocycline answer a long-held question about the drug's potential to help with geographic atrophy. The immune-targeting drug didn't slow the atrophy's expansion across the macula, ...

Researchers from Johns Hopkins University reported yesterday in Nature Neuroscience that they have identified two sets of genes whose decreased expression patterns in key areas of the brain appear to ...

Tiziana Life Sciences (TLSA) announces that the first patient has been dosed with intranasal foralumab in its Phase 2 randomized, ...