BMJ

Type II collagen degradation and its regulation in articular cartilage in osteoarthritis

3 Faculty of Veterinary Medicine, Department of Clinical Sciences, University of Montreal, Ste-Hyacinthe, Quebec, Canada 4 Department of Orthopaedic Surgery, Jewish General Hospital, Montreal, Quebec, ...
BMJ

Infections and the risk of incident giant cell arteritis: a population-based, case-control study

Objectives Alterations in the immune system and infections are suspected to increase susceptibility to giant cell arteritis (GCA). Recently herpes zoster has been directly implicated in the ...
BMJ

The cathelicidins LL-37 and rCRAMP are associated with pathogenic events of arthritis in humans and rats

3 Rheumatology Unit, Department of Medicine at the Karolinska University Hospital Solna, Sweden 4 Division of Rheumatology, Department of Internal Medicine 3, Medical University of Vienna, Vienna, ...
BMJ

The minimally important difference and patient acceptable symptom state for the Raynaud's condition score in patients with Raynaud's phenomenon in a large randomised controlled ...

1 Division of Rheumatology, Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California, USA 2 MediQuest Therapeutics, Inc, Bothell, ...
BMJ

Methods of tophus assessment in clinical trials of chronic gout: a systematic literature review and pictorial reference guide

Objective To identify methods of tophus measurement for gout studies, summarise the properties of these methods and compile a detailed pictorial reference guide to demonstrate the methods. Methods A ...
BMJ

Thickness of human articular cartilage in joints of the lower limb

OBJECTIVES (a) To determine the topographical variations in cartilage thickness over the entire surfaces of cadaveric lower limb joints, and (b) to examine the correlations between: cartilage ...
BMJ

Th1 but not Th17 cells predominate in the joints of patients with rheumatoid arthritis

Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan H Yamada, Division of Host Defense, Medical Institute of Bioregulation, Kyushu University, 3-1 ...
BMJ

Moderate vitamin D deficiency is associated with changes in knee and hip pain in older adults: a 5-year longitudinal study

Background Vitamin D is important for bone, cartilage and muscle function but there are few studies on its association with joint pain. Objective To investigate whether serum vitamin D predicts change ...
BMJ

Anti-adalimumab antibodies and adalimumab concentrations in psoriatic arthritis; an association with disease activity at 28 and 52 weeks of follow-up

Objectives To investigate the relationship between antidrug antibodies (ADA), adalimumab concentrations and clinical response in patients with psoriatic arthritis (PsA) during 52 weeks of follow-up.
BMJ

Incidence trend of five common musculoskeletal disorders from 1990 to 2017 at the global, regional and national level: results from the global burden of disease study 2017

Correspondence to Professor Lingyun Sun, Department of Rheumatology and Immunology, Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital, Nanjing 210008, China; ...
BMJ

Diagnostic values of clinical diagnostic tests in subacromial impingement syndrome

OBJECTIVE Subacromial impingement syndrome (SIS) is a frequent cause of shoulder pain. The aim of this study was to investigate the diagnostic values of clinical diagnostic tests, in patients with SIS ...
BMJ

A Phase II study of the efficacy and safety of rontalizumab (rhuMAb interferon-α) in patients with systemic lupus erythematosus (ROSE)

Objectives To examine the safety and efficacy of rontalizumab, a humanised IgG1 anti-interferon α (anti-IFN-α) monoclonal antibody, in patients with moderate-to-severe systemic lupus erythematosus ...