The San Francisco 49ers won't play until Sunday night in Week 17, but other games throughout the week could impact their ...

Brock Purdy has developed into one of the top, young quarterbacks in the NFL, but he's also one of the more generous players ...

The Indianapolis Colts lose to the San Francisco 49ers in NFL Week 16 action on 'Monday Night Football': Score updates, ...

Philip Rivers starts again when he takes on the ferocious 49ers on "Monday Night Football." Here's score, highlights, stats ...

The Indianapolis Colts are now 8-7 on the season after Monday Night's loss to the San Francisco 49ers. This is the Colts ' ...

Brock Purdy and the San Francisco 49ers spoiled Philip Rivers' return to Indianapolis, as they took down the Colts to remain ...

The San Francisco 49ers beat the Indianapolis Colts 48-27, led by Brock Purdy’s 5 TDs. Colin Cowherd asks if the now 11-4 ...

How to watch this week's Monday Night Football game between the San Francisco 49ers and the Indianapolis Colts.

The San Francisco 49ers and Indianapolis Colts meet for Monday Night Football at Lucas Oil Stadium in Indianapolis, Indiana.

The 49ers are coming off a win over the Titans following their bye week, their fourth consecutive win after a loss to the ...

The San Francisco 49ers cannot just walk into Indianapolis and beat the Colts without putting in a good effort; their roster ...

Preview the San Francisco 49ers' NFL Week 16 matchup with the Colts, including live stream, TV channel, odds, and game ...