Crypt-base-columnar cells are continuously dividing intestinal stem cells that generate IECs, which are composed by distinct specialised cell types that play different functions: Enterocytes (in the ...

Drugs that interrupt the death of healthy bone cells and induce the death of cancerous cells located in bones can prevent or reduced cancer associated bone weakness and improve treatment outcomes for ...

The first full-length structures of two heat shock chaperone proteins in a complex reveal the key structural region regulating their function, according to a new study from St. Jude Children's ...

"Science is teamwork. Lone wolves no longer exist," Peter Walter, researcher and professor at the University of California, San Francisco, and former president of the American Society for Biochemistry ...

Neurodegenerative diseases are characterized by the deposition of clumped proteins in the brain and progressive neuronal cell death. Although the causal link between protein aggregates and ...

Chronic diseases like type 2 diabetes and inflammatory disorders have a huge impact on humanity. They are a leading cause of ...

Researchers at the University of Dundee have revealed in the greatest detail yet the workings of molecules called 'protein degraders' which can be deployed to combat what have previously been regarded ...

However, accumulating evidence over the past two decades demonstrates that a biomarker called C-reactive protein —which ...