A new study shows, for the first time, how the human genome folds and moves in 3D over time to control when genes turn on and ...

New 3D genome maps reveal how DNA folding controls gene activity, offering fresh clues into disease and cell function.

After 10 years, members of the 4D Nucleome consortium have successfully completed the first phase of a project that aims to ...

These sequences are extremely prone to mutations and rank among the most functionally important regions in the entire human ...

The human genome contains about 20,000 protein-coding genes, but that only accounts for roughly two percent of the genome. For many years, it was easier for scientists to simply ignore all of that ...

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark ...

Researchers have revealed that so-called “junk DNA” contains powerful switches that help control brain cells linked to ...

What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too ...

The study shows that a long non-coding RNA called CISTR-ACT acts as a master regulator of cell size, influencing how large or ...

A tiny percentage of our DNA—around 2%—contains 20,000-odd genes. The remaining 98%—long known as the non-coding genome, or ...

What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too large or too small are linked to many diseases. Until now, the genetic basis ...

SickKids researchers discovered that a long non-coding RNA, CISTR-ACT, directly regulates cell size. Using gene-editing tools ...