Here’s a tau twist that may take some adapting to. CD4+ and CD8+ T cells, yes, those mercurial executioners of the immune system, may be responsible for the neurodegeneration seen in Alzheimer’s ...

New research published in Brain, Behavior, and Immunity provides evidence that alcohol use disorder triggers a distinct type of immune response in the brain. The findings suggest that excessive ...

Scientists are revealing mroe about why TDP-43 has long been linked to the neurodegenerative disorders Alzheimer's, FTD, and ...

An editorial reviews evidence that periodontitis and oral bacteria may contribute to Alzheimer’s disease via ...

Researchers have found that a specific immune signaling pathway drives ageing-related inflammation and neurodegeneration. The work can help us understand the mechanisms behind ageing-associated ...

Experiments on an ultra-rare genetic mutation that causes neurodegeneration in children have helped uncover a new mechanism ...

Progressive degeneration in a neuronal network: blue represents healthy neurons, while orange and red represent the protein NPTX2. Yellow shows the toxic aggregation of the protein TDP-43. Scientists ...

Nearly two dozen experimental therapies targeting the immune system are in clinical trials for Alzheimer's disease, a reflection of the growing recognition that immune processes play a key role in ...

Heather Rice can recall a moment early in her career that helped shape how she thinks about Alzheimer’s disease. It happened when she was a zoology major at the University of Oklahoma in 2007, after ...

Some viral diseases could possibly contribute to neurodegeneration. Researchers found that certain viral molecules facilitated intercellular spreading of protein aggregates that are hallmarks of brain ...