Active Risk in Investing: Definition, Calculation, and Examples

Learn what active risk is and how to calculate it. Understand the methods to evaluate active risk in portfolios and explore examples of funds outperforming benchmarks.

Gilead Sciences Exercises Option to License Assembly Biosciences’ Helicase-Primase Inhibitor Programs for Recurrent Genital Herpes

FOSTER CITY, Calif. & SOUTH SAN FRANCISCO, Calif., December 22, 2025--Gilead Sciences, Inc. (Nasdaq: GILD) and Assembly ...

BioMarin to Acquire Amicus Therapeutics for $4.8 Billion, Expanding Position as a Leader in Rare Diseases, Accelerating Revenue Growth and Strengthening Financial Outlook

BioMarin Pharmaceutical Inc. (Nasdaq: BMRN) and Amicus Therapeutics (Nasdaq: FOLD) announced today that BioMarin has entered into a definitive agreement to acquire Amicus for $14.50 per share in an ...
technologynetworks

Molecular Movie Captures How a Mitochondrial Enzyme Processes RNA

High-resolution structures explain the mechanism of human PNPase and provide insights into mutations causing hereditary hearing loss and neurological disease. Researchers at the Department of Cell and ...
Phys.org

Enzyme discovered in cyanobacteria can add phosphate groups to therapeutic peptides

Researchers from CIIMAR and the University of Helsinki have discovered a new biochemical modification in natural cyanobacterial products, revealing an unprecedented tool with promising applications in ...
Science Daily

A tiny enzyme may hold the key to safer pain relief

Researchers have uncovered a surprising way the brain switches pain on, revealing that neurons can release an enzyme outside the cell that activates pain signals without disrupting normal movement or ...
Business Wire

Spruce Biosciences Receives U.S. FDA Breakthrough Therapy Designation for Tralesinidase Alfa Enzyme Replacement Therapy (TA-ERT) in Sanfilippo Syndrome Type B (MPS IIIB)

SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Spruce Biosciences, Inc. (Nasdaq: SPRB), a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for neurological ...
Nanowerk

Scientists glimpse how enzymes 'dance' while they work, and why that's important

Focusing on an enzyme in yeast, they demonstrated how contrasts in atomic scale motions impact their function. The method promises unprecedented access to the mechanisms by which biomolecules work, ...
Phys.org

New drug and enzyme class found to have anti-aging properties

Researchers from Queen Mary University of London's School of Biological and Behavioral Sciences, using the simple fission yeast as a model, have shown that the new TOR inhibitor rapalink-1 prolongs ...
Frontiers

Soil-specific enzyme activity provides novel insight into the soil microbial necromass accumulation during sand dune fixation

Introduction: Soil enzymes are critical to plant growth and soil carbon turnover. However, the traditional method of assessing enzyme activity per unit of soil may be insufficient; instead, ...
Frontiers

Fitting soil extracellular enzyme activity into the complex network of abiotic and biotic soil properties often associated with soil health

In this mini review we examine how soil extracellular enzymes play a key role in nutrient cycling, but stress that their activity alone does not fully represent ecosystem processes. We emphasize the ...