DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within ...
A new study shows how histones undergo correct chemical modifications during synthesis to guide new therapies.
One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...
CpG density and epigenetic modification state modulate DNA mechanics, altering its intrinsic compatibility with nucleosome formation.
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New insights into how a molecular gatekeeper controls early protein modification
For years, ETH researchers have been investigating a molecular complex that plays a key role in protein synthesis. They have ...
The centromere is necessary for the transport of chromosomes during cell division and, therefore, for the correct ...
Researchers at ETH Zurich recently explained the role of a molecular complex that orchestrates the production of proteins in ...
Metabolic reprogramming in the tumor microenvironment shapes immune function and therapy resistance, offering insights into ...
At the Friedrich Miescher Institute for Biomedical Research in Basel, Switzerland, mouse geneticist Antoine Peters and his team investigate how ...
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