Open-source software sheds light on cancer's hidden genetic networks

University of Navarra (Spain) researchers have developed RNACOREX, a new open-source software capable of identifying gene ...
Technology Networks

Scientists Built a Map of How Cancer Genes Talk to Each Other

Researchers developed RNACOREX, an open-source tool that maps gene regulation networks by analyzing miRNA–mRNA interactions.
Frontiers

Integrative pan-cancer analysis of UCP family and experimental validation identifies UCP2 as a potential therapeutic target for glioma

Objective: To evaluate the prognosis and therapeutic potential of the UCP family, particularly uncoupling protein 2 (UCP2), in 32 types of cancer through integrated analysis of TCGA and CGGA databases ...
Frontiers

Integrative multi-omics analysis identifies a PTM-related immune signature and IRF9 as a driver in ccRCC

Background: Clear cell renal cell carcinoma (ccRCC) exhibits marked heterogeneity and variable benefit from immune checkpoint inhibitors (ICIs). Post-translational modifications (PTMs) regulate immune ...