CpG density and epigenetic modification state modulate DNA mechanics, altering its intrinsic compatibility with nucleosome formation.

A game-changining achievement in genome science has identified over 140,000 distinct DNA loops in our cells, providing chromosome fold resolution that is among the best ever created. In this ongoing ...

A new study shows, for the first time, how the human genome folds and moves in 3D over time to control when genes turn on and ...

Researchers created the most detailed maps yet of the genome’s three-dimensional organization using human stem cells and ...

New 3D genome maps reveal how DNA folding controls gene activity, offering fresh clues into disease and cell function.

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

After 10 years, members of the 4D Nucleome consortium have successfully completed the first phase of a project that aims to ...

Memorial Sloan Kettering Cancer Center researchers continued to make strides against cancer in 2025. Learn about some of ...

Study reveals 20 DNA markers in fast-twitch muscle that predict age within 4 years and explain why sprinting declines before ...

Advances in natural language processing and large language models have sparked growing interest in modeling DNA, often referred to as the”language of life”. However, DNA modeling poses unique ...

Researchers at The University of Texas MD Anderson Cancer Center have performed a comprehensive evaluation of five artificial intelligence (AI) models trained on genomic sequences, known as DNA ...