AI maps fleeting DNA quadruplexes, revealing paired structures that control genes in healthy cells and cancer.
CpG density and epigenetic modification state modulate DNA mechanics, altering its intrinsic compatibility with nucleosome formation.
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140,000 DNA loops mapped with AI to predict genome folding
A game-changining achievement in genome science has identified over 140,000 distinct DNA loops in our cells, providing chromosome fold resolution that is among the best ever created. In this ongoing ...
In a landmark effort to understand how the physical structure of our DNA influences human biology, Northwestern investigators and the 4D Nucleome Project have unveiled the most detailed maps to date ...
New 3D genome maps reveal how DNA folding controls gene activity, offering fresh clues into disease and cell function.
One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...
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