A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

CpG density and epigenetic modification state modulate DNA mechanics, altering its intrinsic compatibility with nucleosome formation.

A new study challenges what's long been assumed about genetic variants thought to always cause inherited blindness.

Researchers created the most detailed maps yet of the genome’s three-dimensional organization using human stem cells and ...

New 3D genome maps reveal how DNA folding controls gene activity, offering fresh clues into disease and cell function.

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

It's a common storytelling trope: the stubborn foe who is eventually revealed to be a much-needed friend. Biology has its own ...

If stretched out, human DNA would be about 2 meters long. For this long strand to fit inside the cell nucleus, which is about ...

Study finds CRISPR/Cas gene editing causes “chromatin fatigue” – another surprise mechanism by which it can produce unwanted ...

At the Friedrich Miescher Institute for Biomedical Research in Basel, Switzerland, mouse geneticist Antoine Peters and his team investigate how ...