We're living in a moment where science fiction is becoming medical reality. Imagine a world where doctors can simply rewrite ...
Inside cells, DNA twists and coils itself into a variety of different secondary structures—including i-motifs (iMs) and ...
CRISPR biosensors enable real-time health monitoring with attomolar sensitivity, wearable integration, and multiplex ...
Development of bespoke therapies has been a driving goal in medical research. This year, the announcement of the first patient treated with personalized CRISPR therapy, Baby KJ, highlights this ...
Programmable CRISPR tools are turning stem cell biology into something closer to software engineering, shrinking ...
The approved CRISPR-Cas9 gene therapy involves isolating hematopoietic stem cells (HSCs) from SCD patients and using CRISPR-Cas9 gene editing to reactivate fetal hemoglobin (HbF) genes that are ...
Most approved gene therapies today, including those involving CRISPR-Cas9, work their magic on cells removed from the body, after which the edited cells are returned to the patient. This technique is ...
Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins are core components of fast-evolving therapeutic gene editing tools. Scientists have used CRISPR ...
Scientists introduced CRISPR to the world as a gene-editing tool in summer 2012, when landmark papers from two independent groups demonstrated how the system could be wielded to make cuts in DNA. Now, ...