Positional (or map-based) cloning techniques are widely used to identify the protein products of genes defined by mutation. In Arabidopsis the information generated by the Genome Initiative is giving ...

Maize is one of the most important cereal crops in the world. The complete genome of maize has been sequenced, but its size and complexity presents a challenge to researchers seeking to identify ...

Retinitis pigmentosa (RP), a progressive degeneration of the retina with bone spicule-like pigment deposits, is one of the most frequent hereditary causes of blindness. The disorder is genetically ...

(A) Recombination mapping: the coloured horizontal bars indicate introgressed chromosomes. The vertical orange bar marks the position of the gene that is responsible for hybrid sterility (e.g., the ...

We report here the molecular cloning of an ≈ 1-Mb region of recurrent amplification at 20q13.2 in breast cancer and other tumors and the delineation of a 260-kb common region of amplification.

Positional cloning is a genetic mapping technique used to pinpoint the location of specific traits of interest, such as disease-causing genes or mutations, within the genome. Very simply, this ...

Positional cloning is a genetic mapping technique used to pinpoint the location of specific traits of interest, such as disease-causing genes or mutations, within the genome. Very simply, this ...