DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes.

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

A dissertation study at the University of Jyväskylä (Finland) developed two-dimensional fishnet-like structures from DNA ...

Scripps Research scientists have discovered how some tumors endure DNA damage, revealing a potential new way to target them. The DNA inside our cells is constantly exposed to damage, and one of the ...

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes.

Inside every human cell, six feet of DNA folds into a nucleus that is only a few micrometers wide, yet still manages to ...

The findings may have important implications for diseases linked to mitochondrial dysfunction. A newly identified form of DNA damage inside mitochondria, the small structures that supply energy to our ...

A cutting-edge therapy using base-edited immune cells is offering a major breakthrough for patients with one of the toughest ...