Studies of the genomic DNA compaction in the cell nucleus and dynamic reorganization during physiologic processes or disease development in live cell environment are exceedingly challenging. This ...

Scientists led by Dr. Salvador Aznar-Benitah, head of the Stem Cells and Cancer laboratory at IRB Barcelona, have described the alterations that occur during mammary gland formation when ...

Mitotic chromosomes are pivotal for the inheritance of genetic material. Now, it is already known that chromosomes vary in dimensions among organisms. But what governs mitotic chromosomal size and ...

In response to DNA damage, chromatin undergoes a global decondensation process that has been proposed to facilitate genome surveillance. However, the impact that chromatin compaction has on the DNA ...

A game-changining achievement in genome science has identified over 140,000 distinct DNA loops in our cells, providing chromosome fold resolution that is among the best ever created. In this ongoing ...

Inside every human cell, six feet of DNA folds into a nucleus that is only a few micrometers wide, yet still manages to switch genes on and off with exquisite precision. The latest work on ...

A research team have discovered a mechanism of flowering plant sperm compaction and gathered clues as to why it is required. Sperm cells have compact bundles of DNA, yet exactly how and why sperm cell ...

KANAZAWA, Japan, April 3, 2025 /PRNewswire/ -- Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University and colleagues have achieved a breakthrough in understanding sperm DNA ...

Small basic proteins present in most Archaea share a common ancestor with the eukaryotic core histones. We report the crystal structure of an archaeal histone-DNA complex. DNA wraps around an extended ...