Immune cells (NK and cytotoxic T cells) are activated by short-synthetic mRNA which binds to the ZC3H12D receptor and is transported to the nucleus where it induces the expression of GZMB, a key ...

In today’s rapidly evolving scientific landscape, eliminating barriers to progress is more critical than ever. Precision medicine and targeted therapies hold great promise but are dependent on the ...

The approval of messenger RNA (mRNA) based COVID-19 vaccines marked a pivotal scientific milestone, establishing mRNA as an innovative drug modality with immense therapeutic potential. However, due to ...

Changing just one atom in a COVID-19 vaccine lipid redirects delivery from the liver to the spleen, improving tumor ...

A pandemic concentrates the mind wonderfully. Ever since the COVID-19 pandemic struck, government, academia, business, and the general public have demonstrated an intense interest in mRNA technologies ...

WASHINGTON (AP) — So-called mRNA vaccines saved millions of lives during the COVID-19 pandemic — and now scientists are using that Nobel Prize-winning technology to try to develop vaccines and ...

In principle, mRNA vaccines are ideal for health emergencies as they can be quickly mass produced using a template. The problem is that current cell-based template production methods take too long, ...

Biomedical engineers at Duke University have demonstrated a new synthetic approach that turbocharges bacteria into producing more of a specific protein, even proteins that would normally destroy them, ...