EurekAlert!

SOX9 overexpression ameliorates metabolic dysfunction-associated steatohepatitis through activation of the AMPK pathway

Our findings demonstrate that SOX9 overexpression alleviates hepatic lipid accumulation in MASH by activating the AMPK pathway. These results highlight SOX9 as a promising therapeutic target for ...
ascopubs.org

Use of proteomic analysis of LKB1/AMPK/mTOR pathways to identify IGF-1R pathway upregulation with LKB1 loss or mTOR inhibition in NSCLC: Implications for targeted combinations.

Evaluation of EZH2 SNPs in cholangiocarcinoma patients. This is an ASCO Meeting Abstract from the 2012 ASCO Annual Meeting I. This abstract does not include a full text component.
EurekAlert!

Aging | Isoform-specific AMPK repression affects cognitive function in aged mice

BUFFALO, NY- March 7, 2023 – Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) published a new research paper in Volume 15, Issue 4, entitled, “Isoform-specific ...
FOX8 Cleveland

NovoMedix Presents New Preclinical Data on NMX2 at the 2022 American Heart Association (AHA) Scientific Sessions Meeting

SAN DIEGO, Nov. 7, 2022 /PRNewswire/ -- NovoMedix, LLC ("NovoMedix"), a biotechnology company developing novel, multi-pathway modulators for fibrosis and cancer, today announced the presentation of ...
GEN

Energy Regulator AMPK’s Role in Neuronal Survival

This graphic illustration of a study in Cell Reports shows how a molecular energy regulator in cells, AMPK, is required for astrocytic glycoses, lactate production and lactate shuttle to bio-energize ...
Kaleido Scope

Time-restricted feeding promotes muscle function through purine cycle and AMPK signaling in Drosophila obesity models

Melkani’s lab study, titled "Time-restricted feeding promotes muscle function through purine cycle and AMPK signaling in Drosophila obesity models,” was recently published in Nature Communications.