EurekAlert!

SOX9 overexpression ameliorates metabolic dysfunction-associated steatohepatitis through activation of the AMPK pathway

Our findings demonstrate that SOX9 overexpression alleviates hepatic lipid accumulation in MASH by activating the AMPK pathway. These results highlight SOX9 as a promising therapeutic target for ...
ascopubs.org

Use of proteomic analysis of LKB1/AMPK/mTOR pathways to identify IGF-1R pathway upregulation with LKB1 loss or mTOR inhibition in NSCLC: Implications for targeted combinations.

Evaluation of EZH2 SNPs in cholangiocarcinoma patients. This is an ASCO Meeting Abstract from the 2012 ASCO Annual Meeting I. This abstract does not include a full text component.
EurekAlert!

Aging | Isoform-specific AMPK repression affects cognitive function in aged mice

BUFFALO, NY- March 7, 2023 – Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) published a new research paper in Volume 15, Issue 4, entitled, “Isoform-specific ...
Kaleido Scope

Time-restricted feeding promotes muscle function through purine cycle and AMPK signaling in Drosophila obesity models

Melkani’s lab study, titled "Time-restricted feeding promotes muscle function through purine cycle and AMPK signaling in Drosophila obesity models,” was recently published in Nature Communications.
FOX8 Cleveland

NovoMedix Presents New Preclinical Data on NMX2 at the 2022 American Heart Association (AHA) Scientific Sessions Meeting

SAN DIEGO, Nov. 7, 2022 /PRNewswire/ -- NovoMedix, LLC ("NovoMedix"), a biotechnology company developing novel, multi-pathway modulators for fibrosis and cancer, today announced the presentation of ...
GEN

Energy Regulator AMPK’s Role in Neuronal Survival

This graphic illustration of a study in Cell Reports shows how a molecular energy regulator in cells, AMPK, is required for astrocytic glycoses, lactate production and lactate shuttle to bio-energize ...