For thousands of Americans, opioids no longer relieve pain—they cause pain. Known as "opioid tolerance," patients eventually become desensitized to opioids and more sensitive to pain after years of ...

WASHINGTON — New studies reveal that a learned compensatory response can trigger "drug tolerance," a physiological process central to addiction. Drug tolerance makes people need more and more drug to ...

As the opioid epidemic has picked up wide spread national media attention, so has patient awareness on the topic. One to two years ago when I would try to discuss the ongoing epidemic with patients, ...

Editor’s Note: This is Part 2 of a three-part series looking into the opioid epidemic across the U.S., rehabilitation options in Weld County and stories from people who have overcome or are currently ...

Morphine and other opioids are vital to treat severe and chronic pain. However, they have two problems—prolonged use creates morphine tolerance, where ever-increasing doses are needed for the same ...

This is another one of the basic questions I get regarding addiction. It seems that people think about physical addiction and psychological addiction as somehow separate processes. I think this ...

At the cellular level, pain and pain relief are caused by two different signaling pathways. But the two pathways aren't necessarily independent of one another, according to a study published by ...

Although similar, there are telling differences between food and alcohol addiction. For example, over time, a person builds up a level of alcohol tolerance. In other words, a person needs more alcohol ...

There is a link between all mental health conditions and addiction, including obsessive-compulsive disorder (OCD). People with OCD may turn to substances or behaviors that provide an escape from their ...