Mutations in 3 genes (SPG4, SPG3, and SPG31) are implicated in one half of the autosomal dominant hereditary spastic paraplegias, which are part of the larger group of hereditary spastic diplegias ...

Hereditary spastic paraplegia (HSP), also known as familial spastic paraparesis, is a term used for a group of inherited diseases that affect the upper motor neurons traveling from the brain through ...

Since she was born 20 years ago, Sylva Eugenie Davis of Kansas City has not been able to use her arms or legs. The nerve tracts in the neck region of her spinal cord were injured at birth, causing ...

Mike Wolanin | The Republic Kyle Alumbaugh demonstrates how he uses his wheelchair ramp participate in 5k run, walk or roll to raise awareness for Hereditary Spastic Paraplegia and Primary Lateral ...

Patients with spastic paraplegia type 15 develop movement disorders during adolescence that may ultimately require the use of a wheelchair. In the early stages of this rare hereditary disease the ...

Hereditary spastic paraplegia (HSP) comprises a heterogeneous group of neurodegenerative disorders that are mainly characterised by progressive spasticity and weakness of the lower limbs. Recent ...

A joint study conducted by the University of Bonn and the DZNE has confirmed early-stage brain inflammation in mice. Patients with spastic paraplegia type 15 develop movement disorders during ...

MATTOON -- The Kiwanis Spastic Paralysis Research Foundation offers grant funding for medical research and financial support for a youth summer camp, among its charitable efforts. Members of the ...

There is no cure for the rare disease Hereditary Spastic Paraplegia (HSP), but researchers from Drexel University's College of Medicine and the UMass Chan Medical School have achieved ...

Hereditary Spastic Paraplegia (HSP) encompasses a heterogeneous group of genetic neurodegenerative disorders primarily characterised by progressive lower-limb spasticity and weakness. The condition ...