Researchers at the Icahn School of Medicine at Mount Sinai have characterized how cellular senescence—a biological process in ...

Explore the connection between neurodegeneration and cellular senescence in understanding brain structure and ageing.

Researchers at the Icahn School of Medicine at Mount Sinai have characterized how cellular senescence—a biological process in which aging cells change ...

T cell senescence occurs in the TME, affecting cancer prognosis and immunotherapy efficacy. The TME induces T cell senescence through multiple pathways, including persistent stimulation by ...

There exists a complex synergistic relationship among cancer, circadian rhythms, and aging: aging is a major risk factor for cancer, disruption of circadian rhythms promotes tumor initiation and ...

After a finite number of divisions, cells simply give up. As each round of replication trims their telomeres—the protective caps at the chromosome ends—those caps eventually become too short to ...

Demonstrates how dual-purpose therapeutic targets may address both hepatocellular carcinoma progression and cellular ...

Demonstrates how dual-purpose therapeutic targets may address both hepatocellular carcinoma progression and cellular senescence ...

Leaf senescence determines the duration of photosynthesis, nutrient remobilization efficiency, and ultimately crop yield and ...

Scientists are unraveling the role of senescent cells in a common form of epilepsy, and it could point to new treatments.