Four tiny 3D organs connected themselves in a lab dish, forming a replica of the human pain pathway, in a new study. The discovery allows scientists to better understand chronic pain and how pain ...

Researchers integrated four organoids that represent the four components of the human sensory pathway, along which pain signals are conveyed to the brain. Stimulation of the sensory organoid (top) by ...

Humanoid robots are starting to gain something that once belonged firmly in the realm of science fiction: a sense of pain.

So when you touch a hot stove, the nerve endings in your fingers react instantly. But the ouch comes a split-second later, when that information finally reaches your brain. Well, now, scientists have ...

The hormone estrogen—which female animals typically have more of than males—triggers a molecular cascade in the gut that ...

Scientists have discovered a brain circuit that gives pain its emotional sting, explaining why some hurts linger as suffering. The breakthrough challenges our beliefs about how we process pain and may ...

Men and women experience pain differently, and until now, scientists didn’t know why. New research says it may be in part due to differences in male and female nerve cells. Pain-sensing nerve cells ...

Without the ability to feel pain, life is more dangerous. To avoid injury, pain tells us to use a hammer more gently, wait for the soup to cool, or put on gloves in a snowball fight. Those with rare ...

Forbes contributors publish independent expert analyses and insights. I am a physician and behavioral scientist at Duke University. We all know what “a complainer” is: it’s a person who finds the dark ...

Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes, and ...

Scientists created a model of the human pain pathway in a dish by connecting four separate brain organoids. The feat should help them understand sensory disorders like those affecting pain perception.