Parents, have you ever heard of osteogenesis imperfecta? This is a disease that often attacks bones. This disorder can attack children from birth. Osteogenesis imperfecta also has many types with ...

Mutations in the genes COL1A1, COL1A2, CRTAP, and P3h2 result in OI. In most cases, the inheritance pattern is autosomal dominant and, in some cases, it could also be autosomal recessive. The gene ...

To date, muscle function, and in particular that of the lower extremity, in OI type IV has not been investigated systematically. This study now assesses upper and lower extremity muscle function ...

The type I collagenopathies are a group of heterogeneous connective tissue disorders, that are caused by mutations in the genes encoding type I collagen and include specific forms of osteogenesis ...

Osteogenesis imperfecta type 3 is an inherited (genetic) bone disorder that is present at birth, according to John Hopkins Medicine, which notes that it is a lifelong condition. Furthermore, there is ...

Osteogenesis imperfecta is a clinically and genetically heterogeneous group of inherited connective tissue disorders in which bone fragility is the predominant feature. Cultured dermal fibroblasts ...

Brittle bone disease is a disorder that results in fragile bones that break easily. It’s present at birth and usually develops in children who have a family history of the disease. The disease is ...