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NFL Week 18 early picks against spread

NFL Week 18: Picks, predictions and odds for every game

It's Week 18 of the 2025 NFL season and the regular season comes to a close with plenty to play for around the league.

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· 15h · on MSN

Buccaneers vs. Panthers prediction, odds, start time: NFL Week 18 Saturday picks by model on 53-37 run

SportsLine · 14h

NFL odds, lines, spreads: 2025 Week 18 picks, predictions from proven model: 5-way parlay pays nearly 25-1

Seahawks vs. 49ers prediction, pick, odds for Saturday's NFL Week 18 game - 1/3/2026

Best bets are available as the Seattle Seahawks (13-3) bring a six-game winning streak on the road January 3, 2026 against a streaking San Francisco 49ers squad (12-4), who have won six straight.

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Seahawks and 49ers done big disservice by NFL with schedule decision

2025 NFL Week 18 schedule: Dates, times, channels, how to watch

Seahawks bold predictions for NFC West decider against 49ers

Darnold became just the fifth quarterback in NFL history to have back-to-back 13-win seasons.

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Trent Williams' injury update is bad news for 49ers ahead of pivotal game vs. Seahawks

Seahawks sit atop ESPN power rankings heading into Week 18 finale

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Packers at Vikings: Predictions, picks and odds for NFL Week 18 game

USA Today's NFL experts make their picks for a Week 18 showdown between the Minnesota Vikings and Green Bay Packers

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Packers vs Vikings picks, predictions, odds for NFL Week 18 game Sunday

NFL Week 18 odds, picks, predictions, TV channel, streaming information for the Sunday football game between Green Bay Packers and Minnesota Vikings.