NFL Odds Picks for This Week

Week 18 NFL odds, lines, best bets, predictions

Week 18 NFL odds, lines, best bets, predictions: Computer model backing Packers and Jaguars

All of the updated Week 18 NFL lines are listed below, and SportsLine's advanced computer model has all the NFL betting advice and NFL predictions you need to make the best Week 18 NFL picks now.

· 21h · on MSN

Chargers at Broncos: Predictions, picks and odds for NFL Week 18 game

SportsLine · 18h

NFL odds, lines, spreads: 2026 Week 18 picks, predictions from proven model

· 5h

Seahawks vs. 49ers prediction, pick, odds for Saturday's NFL Week 18 game - 1/3/2026

Best bets are available as the Seattle Seahawks (13-3) bring a six-game winning streak on the road January 3, 2026 against a streaking San Francisco 49ers squad (12-4), who have won six straight.

· 1d

Seahawks and 49ers done big disservice by NFL with schedule decision

· 1d

2025 NFL Week 18 schedule: Dates, times, channels, how to watch

· 9h

Seahawks bold predictions for NFC West decider against 49ers

Darnold became just the fifth quarterback in NFL history to have back-to-back 13-win seasons.

· 10h

Trent Williams' injury update is bad news for 49ers ahead of pivotal game vs. Seahawks

· 15h

Seahawks sit atop ESPN power rankings heading into Week 18 finale

Chargers vs Broncos picks, predictions, odds for NFL Week 18 Sunday

NFL Week 18 odds, picks, predictions, TV channel, streaming information for the Sunday football game between Los Angeles Chargers and Denver Broncos.

3don MSN

Week 17 NFL picks, odds, best bets from proven model: This 5-leg parlay pays over 25-1

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model entered Week 17 on a 53-37 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.