NFL Week 18 early picks against spread
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Sam Farmer makes his picks and predictions for the final week of the NFL regular season, with the 49ers beat the Seahawks and the Steelers prevailing.
Overall picks to win: 8-8 in Week 17 (173-82-1 for the season) Picks to win with 1-5 confidence: 4-7 (103-64-1) Picks to win with 6-10 confidence: 4-1 (70-18) Overall to cover the spread: 9-6-1 (130-117-9) Cover-the-spread picks with 1-5 confidence: 8-4-1 (107-93-8) Cover-the-spread picks with 6-10 confidence: 1-2 (23-23-1)
The playoff picture across the NFL is coming into focus.
Baker Mayfield and the Bucs were in control of the NFC South midway through the season, but they have lost two in a row including a Week 16 loss to these Panthers and five of their last seven. Yes, the Bucs have had to battle through an inordinate number of injuries to key personnel.
There has been an NFL game every Thursday night since Week 1. But is there a "Thursday Night Football" game tonight?
Week 18 is upon us in the NFL, and the conclusion of the 2025 regular season has many playoff scenarios, including the remaining two spots in the AFC and NFC.