Single molecule microarrays have been used in quantitative proteomics, in particular, single cell analysis requiring high sensitivity and ultra-low limits of detection. In this paper, several image ...

The Lens culinaris agglutinin-reactive fraction of AFP (AFP-L3) is widely used to screen for hepatocellular carcinoma (HCC) in Japan and China. We developed a chemiluminescent protein microarray for ...

Interim Executive Director, Biodesign Institute Director, Biodesign Institute's Virginia G. Piper Center for Personalized Diagnostics; Virginia G. Piper Chair of Personalized Medicine; Pr ...

Scientific advances in the field of genetics and gene-expression profiling have revolutionized the concept of patient-tailored treatment. Analysis of differential gene-expression patterns across ...

Definition: A microarray is a small, flat substrate carrying an ordered grid of microscopic probe features, each containing a known biological molecule, that is used to measure many molecular targets ...

MicroRNAs (miRNAs) are small, short non-coding RNAs that bind to specific messenger RNAs (mRNAs) and regulate gene expression either by degradation or by translational inhibition of the mRNA. miRNAs ...

Microarrays provide a way of organizing biological samples for high-throughput analysis. Samples are arranged in columns and rows upon a support surface consisting of a glass slide, a nitrocellulose ...

Curious about how to detect and characterize tumor-derived biomarkers from liquid biopsy samples? Genomics-based methods now provide access to more molecular data than ever before, delivering cancer ...

Relationship of pro-angiogenic factor Cyr61to colorectal cancer development and prognosis. Background: Microarrays are widely used to study gene expression patterns in cancer. In colorectal cancer, it ...

High-Throughput and Multiplexed Assays Augment Biomarker Discovery and Diagnostics High-throughput proteomics using microarray-based technology and proteome chips is accelerating protein-biomarker ...

This Proven Technology Continues To Find Its Niche in the Modern Molecular Toolkit The advent of microarray technology has a much longer history than many realize. Ask any scientist “What is a ...

Twenty pneumococcal serotyping methods were put to the test. Medical doctors express concern about healthcare quality measures in the United States. Many recently developed pneumococcal serotyping ...