In a recent study posted to the bioRxiv* pre-print server, researchers examined the role of sialic acid-binding immunoglobulin-type lectins-1 (CD169), a myeloid cell-specific receptor, in facilitating ...
During some severe cases of COVID-19, a macrophage-induced cytokine storm occurs, which can lead to lasting tissue damage and poor patient outcomes. However, it is unclear how the SARS-CoV-2 infection ...
Sepsis is a fatal syndrome characterized by life-threatening organ dysfunction originating from a chaotic and unchecked innate immune response to infection. Notably, macrophages are the master ...
Cells have sophisticated methods of sensing stimuli and communicating with nearby cells in response to these stimuli. For example, macrophages can sense environmental stimuli—tissue damage, foreign ...
When cancer cells die, macrophages consume them and produce inflammatory cytokines. This activates JAK and STAT proteins in living cancer cells, enabling them to produce their own Upd3 and creating a ...
BOSTON--(BUSINESS WIRE)--DeepCure, a therapeutics company using AI to discover novel drugs for inflammation and immune diseases, today announced it will present early safety and efficacy data for ...
Immunotherapy, which harnesses our body’s own immune system to fight cancer, has revolutionized modern oncology. Yet despite its success with several cancers, many patients still fail to respond to ...