The World Health Organization (WHO) has published its new 2025 Guidelines on the replacement or removal of animal tests for ...

Endotoxin testing is critical in industries such as biopharmaceuticals and medical devices to ensure product safety and reliability. Endotoxins, which are lipopolysaccharides (LPS) found in ...

Endotoxin refers to a component of the outer cell membrane of Gram-negative bacteria called lipopolysaccharide (LPS). LPS is the biologically active portion of naturally occurring endotoxin complexes.

The Sievers Eclipse BET Platform combines ease-of-use and groundbreaking technology to automate endotoxin assay setup without altering reaction biochemistry or compliance. What it does alter is the ...

The presence of harmful bacteria in parenteral drugs or implantable devices can cause inflammatory responses such as fever and, in some cases, may even be fatal. As a result, robust bacterial ...

In this episode of C&EN Uncovered, host Craig Bettenhausen speaks with C&EN assistant editor Laurel Oldach about the use of horseshoe crab blood in pharmaceutical endotoxin testing, the challenges of ...

In this webinar, attendees will be provided an overview of the technologies that currently exist for bacterial endotoxins testing (BET), and the drawbacks associated with each. Microfluidic technology ...

Lonza has launched the Nebula® Multimode Reader, the first multimode reader qualified for use with Lonza’s turbidimetric, chromogenic and recombinant endotoxin detection methods. Users can now ...

Novel Approach to Achieving Consistent Results with the Limulus Amebocyte Lysate Test The standard tool for screening endotoxins—highly toxic, heat-stable lipopolysaccharides that constitute the outer ...

THE role of bacterial endotoxins in the pathogenesis of infections due to endotoxin-containing bacteria is not clear. It is commonly assumed that endotoxin is a major factor in determining toxicity ...