Las Vegas converted a pair of fourth-down tries on its latest drive, which ended with this touchdown pass from Geno Smith to Tyler Lockett, who tapped the toes in the back of the end zone to come away with the score. The loser of this game will likely land the No. 1 overall pick on the draft.

The San Francisco 49ers finished their Week 16 "Monday Night Football" contest with a 48-27 win over the Indianapolis Colts at Lucas Oil Stadium.

Brock Purdy and the San Francisco 49ers made it look easy against the Indianapolis Colts on "Monday Night Football."

The Week 16 edition of "Monday Night Football" between the Indianapolis Colts (8-7) and the San Francisco 49ers (11-4) will be remembered as the Brock Purdy game. The 49ers quarterback powered San Francisco to a 48-27 road victory with a career-high five passing touchdowns.

A meeting featuring two of the NFL's best in Christian McCaffrey and Jonathan Taylor will close Week 16 as the 49ers and Colts clash in a matchup with playoff implications.