A total of 112 patients with acute hepatic porphyria (AHP), of which 104 have AIP, were enrolled from 13 countries. Updated 12-month data from EXPLORE demonstrate that patients suffer from both acute ...

Porphyria refers to a group of genetic disorders that can affect the nervous system or the skin. Share on Pinterest All types of porphyria are characterized by a slower than normal production of heme.

Please provide your email address to receive an email when new articles are posted on . Clinicians are hoping an RNA interference therapeutic targeting aminolevulinic acid synthase 1, known as ...

Patients with porphyria cutanea tarda have more cutaneous lesions in summer than in winter, but only after prolonged and chronic exposure to light. Some patients excrete red, fluorescent urine during ...

Variegate porphyria (VP) is an autosomal dominant condition that results from the deficiency of protoporphyrinogen oxidase (PPOX, EC 1.3). The build-up of porphyrin precursors delta-aminolevulinic ...

Congenital erythropietic porphyria (CEP), or Gunther's disease, is one of the rarest of the porphyrias, a group of metabolic disorders in which excessive quantities of porphyrins or their precursors ...

Acute porphyria is a group of uncommon diseases that can cause severe, potentially life-threatening attacks of abdominal pain, nausea, vomiting and paralysis. Liver transplantation is currently the ...

Acute hepatic porphyria (AHP) is a rare inherited metabolic disorder caused by a deficiency of the enzymes needed to make haem. It is characterised by high levels of porphyrin precursors, including ...