December 20, 2010 — Replacing host stem cells with donor-derived cells homozygous for the CCR5 gene variant Δ32 (CCR5Δ32/Δ32) resulted in the HIV viral reservoir being reduced over time, strongly ...
Am J Health Syst Pharm. 2009;66(8):715-726. Mechanism of action of maraviroc. Before fusion of the HIV viral envelope and host cell membrane can occur, an HIV glycoprotein complex consisting of ...
A seventh patient has achieved sustained HIV remission after allogeneic hematopoietic stem cell transplantation, according to a new case report. The patient, known as the "next Berlin patient," has ...
A few decades ago, the idea of an HIV cure sounded unrealistic. Today, doctors describe a carefully documented case where the virus appears to be gone for good after a rare stem cell transplant. A ...
A seventh person, dubbed "the next Berlin Patient," appears to be cured of HIV after a stem cell transplant for cancer treatment, according to a report at a press briefing ahead of the International ...
Co announces the presentation of data demonstrating that human CD4 T-cells can be made permanently resistant to HIV infection by treatment with zinc finger DNA-binding protein nucleases and ...
Scientists are testing CRISPR gene editing as a potential HIV cure after successfully removing the virus from infected cells ...
At the cellular level, HIV-1 transmission involves a highly coordinated process whereby the virus binds to CD4 receptors and one of two coreceptors—CCR5 (R5) or CXCR4 (X4)—on host immune cells, ...
A 60-year-old man in Germany has become at least the seventh person with HIV to be announced free of the virus after receiving a stem-cell transplant. But the man, who has been virus-free for close to ...