In recent years, we have come to appreciate that loss or dysfunction of insulin-producing islet beta cells underlies virtually all major forms of diabetes mellitus. In type 1 diabetes, beta cells ...
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Reprogramming immunity to protect beta cells in type 1 diabetes
In the battle against type 1 diabetes (T1D), one researcher at the Medical University of South Carolina (MUSC) is leading a ...
In a clinical trial led by University of Toronto researchers, an allogeneic stem cell–derived islet therapy (zimislecel) restored insulin production and ended severe hypoglycemia in adults with type 1 ...
Borrowing a cancer cell’s disguise, scientists shielded insulin-producing cells from attack by the immune system, a breakthrough that could pave the way for targeted type 1 diabetes treatments without ...
Diabetes researchers and bioinformaticians from the Icahn School of Medicine at Mount Sinai have developed a new understanding of how human beta cell regenerative drugs work. These drugs, developed at ...
Researchers have discovered a novel approach to protecting insulin-producing beta cells from the damaging effects of glucolipotoxicity - a harmful condition linked to the progression of type 2 ...
The beta cells of the pancreas don’t need the assistance of other pancreatic cells to produce insulin, according to new research. The findings are not only a potential game-changer for diabetics, but ...
A recent study identified that a special group of pancreatic beta cells are crucial for triggering the blood sugar response. We know that beta cells of the pancreas play an important role in ...
Pancreatic islets from adult mice. On the left, islet composed of different types of endocrine cells. Right: pancreatic islet composed solely of beta cells. Our glycaemic balance is based on the ...
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