Researchers have discovered an unusual case where two well-known cancer-related mutations—APC and KRAS—coexisted in a woman with familial adenomatous polyposis (FAP) and a history of endometrial ...

The order of cancer-driving mutations—genetic changes—plays an important role in whether tumors in the intestine can develop, new research reveals. Colorectal cancer is the second leading cause of ...

The genetic confirmation of a suspected diagnosis of "hereditary colorectal cancer" is of great importance for the medical care of affected families. However, many of the variants identified in the ...

Colorectal cancer is the second leading cause of cancer-related death globally. Although some of the molecular changes associated with colorectal cancer are known, how they contribute to cancer ...

Researchers have discovered an unusual case where two well-known cancer-related mutations-APC and KRAS-coexisted in a woman with familial adenomatous polyposis (FAP) and a history of endometrial ...

The Institute of Intelligent Medical Research (IIMR) of BGI Genomics, in collaboration with Sweden’s Uppsala University, have uncovered 33 novel mutated driver genes in colorectal cancer (CRC). The ...

Cases of colorectal cancer in younger adults are climbing worldwide, driven by lifestyle changes and inherited genetic risks.